CNSigs: Analysis of Copy Number Signatures

A workflow to generate and analyze signatures based on copy number data using non-negative matrix factorization (NMF) in an approach similar to that used in mutational signatures. It can be used to extract features from Copy number segment data and use that to find a subset of copy number signatures which can be further used to correlate with other relevant data. For more on 'NMF' see Gaujoux (2013) <doi:10.1186/1471-2105-11-367>.

Version: 0.1.0
Depends: R (≥ 2.10), NMF
Imports: methods, doParallel, foreach, flexmix, limSolve, ggplot2, snow, cowplot, pheatmap, RColorBrewer, viridisLite, colorspace, stats, utils
Suggests: knitr, rmarkdown
Published: 2026-01-08
DOI: 10.32614/CRAN.package.CNSigs (may not be active yet)
Author: David Tallman [aut], Shawn Striker [cre, ctb], Daniel Stover [cph]
Maintainer: Shawn Striker <striker.35 at osu.edu>
License: MIT + file LICENSE
NeedsCompilation: no
CRAN checks: CNSigs results

Documentation:

Reference manual: CNSigs.html , CNSigs.pdf
Vignettes: CNSigs.Rnw (source, R code)

Downloads:

Package source: CNSigs_0.1.0.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): CNSigs_0.1.0.tgz, r-oldrel (arm64): CNSigs_0.1.0.tgz, r-release (x86_64): CNSigs_0.1.0.tgz, r-oldrel (x86_64): not available

Linking:

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